drugset / Trial / NCT05400577
Sotorasib in KRAS G12C Mutated, Resectable, Stage Ib-IIIA NSCLC
NaSingle-groupOpen-labelTreatment
Summary
This is a single arm study, conducted at two centers, of neoadjuvant sotorasib in treatment naïve patients with stage Ib-IIIa NSCLC. The study will accrue 25 patients in all. Patients must have been deemed surgically resectable and physiologically fit for surgery by a thoracic surgeon prior to enrollment.
Timeline
- Start
- 2022-07-13
- Primary completion
- 2024-01-01
- Completion
- 2024-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sotorasib | Small molecule | 960 mg | Oral |