drugset / Trial / NCT05400577

Sotorasib in KRAS G12C Mutated, Resectable, Stage Ib-IIIA NSCLC

NCT05400577

Phase 2 Withdrawn Fox Chase Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This is a single arm study, conducted at two centers, of neoadjuvant sotorasib in treatment naïve patients with stage Ib-IIIa NSCLC. The study will accrue 25 patients in all. Patients must have been deemed surgically resectable and physiologically fit for surgery by a thoracic surgeon prior to enrollment.

Timeline

Start
2022-07-13
Primary completion
2024-01-01
Completion
2024-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Sotorasib Small molecule 960 mg Oral