drugset / Trial / NCT05403580

Olanzapine for the Treatment of Chronic Nausea and/or Vomiting in Patients With Advanced Cancer

NCT05403580

Phase 3 Withdrawn Mayo Clinic
RandomizedParallel-groupDouble-blindSupportive care

Summary

This phase III trial compares olanzapine to placebo in decreasing nausea and vomiting in patients with cancer that has spread to other places in the body (advanced). Patients with advanced cancer may experience nausea and/or vomiting that is unrelated to chemotherapy or radiation. Giving olanzapine may help reduce nausea and increase appetite in patients who have advanced cancer.

Timeline

Start
2022-06-03
Primary completion
2023-12-29
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Olanzapine Small molecule Oral