drugset / Trial / NCT05409027
A Study to Assess 11 Beta-hydroxysteroid Dehydrogenase Type 1 Inhibition in Adipose Tissue by SPI-62
NaSingle-groupOpen-labelBasic science
Summary
This will be an exploratory, open-label study of 11β-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibition by SPI-62 in obese subjects with type 2 diabetes mellitus (T2DM)
Timeline
- Start
- 2021-07-23
- Primary completion
- 2022-03-10
- Completion
- 2024-02-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | clofutriben | Small molecule | 1 mg | Oral |
| Subject | clofutriben | Small molecule | 15 mg | Oral |
| Background | Cortisone-d8 | Unknown | 12 ug | Subcutaneous |