drugset / Trial / NCT05412290

Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma

NCT05412290

Phase 1 Active not recruiting 9 enrolled Washington University School of Medicine Genentech, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

This phase 1 pilot study examines the feasibility and safety of mosunetuzumab after autologous stem cell transplant for patients with aggressive B cell lymphomas. Mosunetuzumab is an antibody that has been engineered to attach to two target cells in the immune system: T cells that normally perform tasks like killing virus-infected cells, and cancerous B cells. Mosunetuzumab has been designed to direct these T cells to kill the cancerous B cells instead.

Timeline

Start
2022-12-22
Primary completion
2027-01-31
Completion
2028-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Mosunetuzumab Monoclonal antibody 30 mg Intravenous