drugset / Trial / NCT05417230

RC48-ADC Combinatioed Envolizumab in Locally Advanced or Metastatic Biliary Tract Cancer With Positive HER-2

NCT05417230

Phase 2 Unknown 29 enrolled Jiangsu Cancer Institute & Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study was a prospective, single-arm phase II clinical trial to observe and evaluate the efficacy and safety of RC48-ADC combined envafolimab in the first-line treatment of locally advanced or metastatic biliary tract cancer with positive HER-2.

Timeline

Start
2022-08
Primary completion
2024-08
Completion
2025-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Disitamab Vedotin Monoclonal antibody 2.5 mg/kg Intravenous
Subject Envafolimab Monoclonal antibody 200 mg Subcutaneous

Indications