drugset / Trial / NCT05420350
Lamotrigine and Bupropion for Meniere's Disease
Phase 2
Unknown
34 enrolled
Dent Neuroscience Research Center
Cures Within Reach · collabDent Family Foundation · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a double-blind, placebo-controlled clinical trial to assess whether treatment with lamotrigine and bupropion is more effective than placebo to reduce definitive Meniere's vertigo attacks (DMVA) and dizziness in patients with Meniere's disease. Thirty four participants will be randomized to treatment or placebo groups. Each participant will take part in the trial for 34 weeks, or approximately 9 months.
Timeline
- Start
- 2020-12-16
- Primary completion
- 2024-07
- Completion
- 2024-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupropion | Small molecule | 100 mg | Oral |
| Comparator | Lamotrigine | Small molecule | 125 mg | Oral |