drugset / Trial / NCT05420350

Lamotrigine and Bupropion for Meniere's Disease

NCT05420350

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a double-blind, placebo-controlled clinical trial to assess whether treatment with lamotrigine and bupropion is more effective than placebo to reduce definitive Meniere's vertigo attacks (DMVA) and dizziness in patients with Meniere's disease. Thirty four participants will be randomized to treatment or placebo groups. Each participant will take part in the trial for 34 weeks, or approximately 9 months.

Timeline

Start
2020-12-16
Primary completion
2024-07
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupropion Small molecule 100 mg Oral
Comparator Lamotrigine Small molecule 125 mg Oral

Indications