drugset / Trial / NCT05421663

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

NCT05421663 ↗

Phase 1/2 Active not recruiting 166 enrolled Janssen Research & Development, LLC
NaSingle-groupOpen-labelTreatment

Summary

This is a Phase 1b/2, multicenter, open-label, study of prizloncabtagene autoleucel (prizlo-cel), an autologous dual targeting chimeric antigen receptor (CAR) T-cell therapy targeting both cluster of differentiation (CD) CD20 and CD19, for the treatment of adult participants with relapsed or refractory (r/r) B-Cell non-Hodgkin lymphoma (B-NHL) or frontline high-risk diffuse large B-cell lymphoma (DLBCL).

Timeline

Start
2022-08-12
Primary completion
2028-12-29
Completion
2041-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Prizloncabtagene Autoleucel Cell therapy — Intravenous