drugset / Trial / NCT05430048
Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
RandomizedParallel-groupTriple-blindTreatment
Summary
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative adhesions and scarring and even severe orbital and brain injury In the current study we will investigate the effect of nasal desmopressin versus oral bisoprolol for controlling bleeding and improving surgical field clarity during functional endoscopic sinus surgery
Timeline
- Start
- 2022-07-01
- Primary completion
- 2022-10-30
- Completion
- 2022-11-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bisoprolol | Other / unclassified | 2.5 mg | Oral |
| Comparator | Desmopressin | Peptide | 10 ug | Intranasal |