drugset / Trial / NCT05431153

A Study to Investigate the Effect of Tablet Formulation and Food on PF-07104091 in Healthy Participants

NCT05431153

Phase 1 Completed 30 enrolled Pfizer
RandomizedCrossoverOpen-labelBasic science

Summary

This is a single dose crossover pharmacokinetic (pharmacokinetics helps in understanding how the drug is changed and eliminated from the body after a participant takes it) study in healthy participants. The study consists of 5 treatments, and each participant will be randomized to receive 4 of the treatments in separate periods in a specific sequence. Each treatment consists of a single dose of PF-07104091 and the treatments differ by tablet formulation and/or whether the dose is to be given under fasted or fed conditions. Plasma pharmacokinetics of PF-07104091 will be assessed following each dose to determine the effect of tablet formulation and fed condition on the relative bioavailability of PF-07104091.

Timeline

Start
2022-06-10
Primary completion
2022-10-17
Completion
2022-10-17

Drugs

EvaluationDrugModalityDoseRoute
Subject TEGTOCICLIB Small molecule Oral

Indications

No indication recorded.