drugset / Trial / NCT05434624

QT Distance and P Dispersion in ECG in Patients Having Bronchoscopy in the ICU

NCT05434624 ↗

Unknown 40 enrolled Abant Izzet Baysal University
RandomizedParallel-groupOpen-labelTreatment

Summary

Fiberoptic bronchoscopy (FOB) is one of the most useful procedures for diagnosing and treating respiratory illnesses to figure out symptoms like hemoptysis, wheezing, or cough. Furthermore, FOB is a frequent method, in intensive care units, for both diagnoses of ventilator-associated pneumonia (VAP) and treatment of atelectasis with bedside sedation.) Propofol is often used in anesthesia for endoscopic treatments. Using propofol for deep anesthesia may be indicated to prevent the patient from feeling discomfort before FOB and to reduce the chance of complications. Although major complications of FOB such as hypoxia and pneumothorax are known, there are limited studies showing its effects on cardiac hemodynamics. The cardiac effects of laryngoscope and intubation were investigated by using different anesthetic agents. In this study, we evaluated the effect of bronchoscopy with BIS-controlled sedation on ECG in ICU patients by monitoring the QT interval and P interval.

Timeline

Start
2022-06-25
Primary completion
2023-12-25
Completion
2024-03-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Propofol Small molecule 60 ug/kg —
Background Midazolam Small molecule — Intravenous

Indications