drugset / Trial / NCT05435274

Phase 1/2 Study of HS-10376 in Patients With Non-Small Cell Lung Cancer

NCT05435274 ↗

Phase 1/2 Unknown 380 enrolled Jiangsu Hansoh Pharmaceutical Co., Ltd.
NaSequentialOpen-labelTreatment

Summary

HS-10376 is an oral, highly selective, small molecular inhibitor of EGFR/HER2 Exon 20 insertion mutation. This study will evaluate the safety, tolerability, pharmacokinetics and clinical activity of HS-10376 in Chinese advanced Non-Small Cell Lung Cancer (NSCLC) patients.

Timeline

Start
2021-09-30
Primary completion
2024-10-07
Completion
2025-10-07

Drugs

EvaluationDrugModalityDoseRoute
Subject HS-10376 Small molecule — Oral