drugset / Trial / NCT05438550

14-day Double Therapy Versus Bismuth Quadruple Therapy in First-line Treatment of Helicobacter Pylori Infection

NCT05438550

Phase 4 Unknown 258 enrolled Shandong University
RandomizedParallel-groupOpen-labelTreatment

Summary

The researchers collected untreated H. pylori positive patients from outpatient clinics. Subjects were randomized to 14 days of dual therapy with Tegoprazan or 14 days of quadruple therapy with bismuth for eradication. At 6 weeks after treatment, subjects underwent another 13C-urea breath test. The eradication rate, adverse reaction rate and patient compliance were calculated.

Timeline

Start
2023-02-14
Primary completion
2023-12-20
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 750 mg
Subject Tegoprazan Other / unclassified 50 mg