drugset / Trial / NCT05444036

Caudal Ketamine-bupivacaine More Effective Than Bupivacaine-saline

NCT05444036

Phase 1 Completed 60 enrolled Egymedicalpedia
RandomizedParallel-groupSingle-blindTreatment

Summary

Because pain is difficult to measure in children, post-operative pain is frequently undertreated in this age range. Pain treatment is required in children due to the high emotional component of pain. Pain is a multidimensional, subjective, perceptual event having a variety of qualities such as intensity, quality, time course, and effects that are perceived differently by each person. Because the operational definition of pain necessitates self-report, pain experienced by children and babies is frequently overlooked, if not ignored. When general anesthesia is paired with regional procedures, children of all ages are exposed to less intravenous and inhalational anesthetics and analgesics, leaving them nearly free of nausea, vomiting, itching, or unneeded drowsiness. Being completely awake and able to drink soon after surgery, as well as having no issues breathing even after lengthy surgery, are significant benefits that children and parents value.

Timeline

Start
2018-09-01
Primary completion
2019-05-15
Completion
2019-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.5 mg/kg Other

Indications

No indication recorded.