Effects of Oxytocin Administered Orally Using a Medicated Lollipop on Peripheral Concentrations and Attention

Unknown 72 enrolled University of Electronic Science and Technology of China

RandomizedParallel-groupTriple-blindBasic science

Summary

The study will investigate whether oxytocin (24IU) administered orally using medicated lollipops results in increased peripheral oxytocin concentrations and can modulate social attention in an anti-saccade paradigm in the same way as when it is administered by intranasal or lingual routes.

Timeline

Start: 2022-04-01
Primary completion: 2022-07-30
Completion: 2022-08-30

Publications

Background Xu X, Li J, Chen Z, Kendrick KM, Becker B. Oxytocin reduces top-down control of attention by increasing bottom-up attention allocation to social but not non-social stimuli - A randomized controlled trial. Psychoneuroendocrinology. 2019 Oct;108:62-69. doi: 10.1016/j.psyneuen.2019.06.004. Epub 2019 Jun 15.
Background Zhuang, Q., Zheng, X., Yao, S., Zhao, W., Becker, B., Xu, X., et al. (2022). Oral, similar to intranasal, administration of oxytocin decreases top-down social attention. medRxiv, 2021.09.20.21263870. doi: 10.1101/2021.09.20.21263870.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oxytocin	Peptide	24 iu	Oral

Indications

No indication recorded.