drugset / Trial / NCT05445804

Oral Cannabidiol for Tobacco Cessation

NCT05445804

RandomizedCrossoverTriple-blindBasic science

Summary

Cannabidiol is a compound found in cannabis plants that is well tolerated, has low abuse liability, and might be an effective medication to promote tobacco cessation. This clinical study will use a validated approach for screening tobacco cessation medications to determine if oral cannabidiol increases short-term tobacco abstinence, and evaluate mechanisms that might explain how cannabidiol alters smoking behavior. Results from this study will provide data on the therapeutic potential of cannabidiol for tobacco cessation.

Timeline

Start
2022-11-01
Primary completion
2026-12-01
Completion
2027-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabidiol Other / unclassified 300 mg Oral
Subject Cannabidiol Other / unclassified 600 mg Oral

Indications