The Effects of a Ruminococcus Torques Strain Bacterium in Healthy Adults.

Completed 32 enrolled Oluf Pedersen Technical University of Denmark · collab University Hospital, Gentofte, Copenhagen · collab University of Copenhagen · collab

RandomizedCrossoverQuadruple-blindOther

Summary

A randomized, placebo controlled crossover study investigating the potential metabolic effects of the naturally occurring gut microbe Ruminococcus torques in healthy, overweight adults.

Timeline

Start: 2023-05-03
Primary completion: 2023-09-06
Completion: 2023-09-14

Outcome

Missed primary endpoint

paper We found no effects on the primary endpoint of the trial. PMID 42464306 ↗

Publications

Gaede J, Fan Y, Lyu L, Stankevic E, Gasbjerg LS, Rossing P, Oresic M, Hyotylainen T, Brix S, Lund AB, Olsen DA, Petersen ERB, Brandslund I, Hartmann B, Holst JJ, Knop FK, Pedersen O. A short-term randomized clinical trial testing feasibility of and physiological responses to a Ruminococcus torques strain in healthy overweight humans. Genome Med. 2026 Jul 16. doi: 10.1186/s13073-026-01708-9. Online ahead of print.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ruminococcus torques	Other / unclassified	1e+11 cells	Other