drugset / Trial / NCT05455359

Gastrointestinal Dysmotility on Aspiration Risk

NCT05455359

Phase 4 Recruiting 120 enrolled Boston Children's Hospital
RandomizedCrossoverTriple-blindTreatment

Summary

The hypothesis of this study is that esophageal and gastric dysmotility increase the risk of developing aspiration-associated symptoms in children with neurologic impairment. The investigators are conducting a ten week cross over study comparing prucalopride to famotidine for the treatment of aspiration-associated symptoms.

Timeline

Start
2025-02-13
Primary completion
2027-05-31
Completion
2027-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Famotidine Other / unclassified 0.4 mg/kg
Subject Prucalopride Small molecule 0.04 mg/kg