drugset / Trial / NCT05455372

Influence of Oral Hp Infection and Oral Related Factors on Gastric Hp Infection and Eradication Therapy

NCT05455372

Non-randomizedParallel-groupOpen-labelPrevention

Summary

Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric cancer and other diseases. The discovery and eradication of H. pylori is of great significance for the prevention and treatment of related diseases. Oral H. pylori may act as a "reservoir" to cause H. pylori to spread between populations and to cause individual gastric H. pylori infection and recurrence.Understanding the oral and gastric H. pylori infection and influencing factors of the population can provide scientific basis for the formulation of local H. pylori infection prevention strategies.Analyzing the influencing factors of H. pylori eradication in the population can improve the local H. pylori eradication rate and reduce the recurrence of H. pylori infection.Therefore, this study intends to analyze the influence of oral H. pylori infection and oral related factors on gastric H. pylori infection and eradication therapy in outpatients of a tertiary hospital in Xi'an.

Timeline

Start
2022-07-08
Primary completion
2023-09-30
Completion
2024-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 1000 mg
Subject Clarithromycin Small molecule 500 mg
Subject Ilaprazole Small molecule 5 mg
Subject colloidal bismuth tartrate Unknown 220 mg