ENSO 16 - Study in Healthy Subjects

Summary

The objective of this study is to evaluate differences in glucose metabolism parameters after oral administration of 30g glucose or 30g ENSO16. Blood samples will be be collected from 15 male or female subjects at defined time points (0 - 15 - 30 - 45 - 60 - 90 - 120 \- 180 minutes; 3 min at each time point). Individual plasma glucose, insulin and C-peptide concentrations are going to be evaluated and statistically assessed. Subjects will also be asked to complete a questionnaire regarding their digestion after oral intake of ENSO 16 or glucose defined timepoints.

Timeline

Start

2022-04-28

Primary completion

2022-06-14

Completion

2022-07-29

Publications

• Lutnik M, Weisshaar S, Mussbacher LM, Steiner D, Wolzt M. The substitute ENSO 16 has low impact on glucose metabolism in healthy humans: a randomized, double-blind, active-controlled, cross-over trial. Sci Rep. 2024 Jun 24;14(1):14534. doi: 10.1038/s41598-024-65560-w.

Drugs

Indications