drugset / Trial / NCT05461820

Effects of Different Treatment Schemes on the Regulation and Recurrence of Graves' Disease

NCT05461820

RandomizedParallel-groupOpen-labelTreatment

Summary

In this study, the dose of methimazole was adjusted according to the different states of thyroid function, and the effects of conventional therapy and intensive therapy on the cumulative recurrence of Graves' hyperthyroidism after two years of drug withdrawal were evaluated. At the same time, the changes of immune indexes and inflammatory factors in the regulation process were evaluated. This study is a phase IV clinical study designed and carried out by the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), which is a randomized, open and routine treatment group with parallel control.

Timeline

Start
2018-05-01
Primary completion
2023-12-31
Completion
2030-07-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Methimazole Small molecule 15 mg
Comparator Methimazole Small molecule 30 mg

Indications