drugset / Trial / NCT05469165
Serotonin Receptor Blockers in Ischemic Mitral Regurgitation
Phase 2
Recruiting
214 enrolled
Laval University
Canadian Institutes of Health Research (CIHR) · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This study is intended to investigate the effect of cyproheptadine (a 5HT2B receptor blocker) on mitral regurgitation severity.
Timeline
- Start
- 2023-06-20
- Primary completion
- 2026-09
- Completion
- 2027-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyproheptadine | Small molecule | 0.5 mg/kg | Oral |