drugset / Trial / NCT05469347
Alirocumab in Patients with Sepsis
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine whether the drug alirocumab, which may lower cholesterol, can reduce the amount of inflammation caused by an infection that has caused either low blood pressure or difficulty breathing. Participants will be randomized to receive a single IV infusion of alirocumab or a placebo.
Timeline
- Start
- 2023-01-04
- Primary completion
- 2025-02-18
- Completion
- 2025-02-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alirocumab | Monoclonal antibody | 600 mg | Intravenous |