The Effect of Dienogest vs. Norethindrone Acetate Treatment in Endometriosis

Summary

This randomized controlled study aims to investigate the efficiency of medical treatment modalities in endometriosis patients. The study protocol involves two arms. (Dienogest Group and Noretindrone Acetate Group). The patients diagnosed with endometriosis are randomized depending on their protocol ids. The Dienogest group is prescribed 5 mg dienogest per day and neta group is prescribed 5 mg neta per day. The pain scores will be analyzed six months and twelve months after treatment.

Timeline

Start

2021-04-01

Primary completion

2023-05-30

Completion

2023-06-30

Publications

• Gurbuz TB, Aslan K, Kasapoglu I, Muzii L, Uncu G. Norethindrone acetate versus dienogest for pain relief in endometriosis related pain: A randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2025 Jun;310:113940. doi: 10.1016/j.ejogrb.2025.113940. Epub 2025 Mar 29.

Drugs

Indications