drugset / Trial / NCT05480657

Safety, Tolerability, and Efficacy of Immunomodulation With AT-1501 in Combination With Transplanted Islet Cells in Adults With Brittle T1D

NCT05480657

Phase 1/2 Withdrawn Eledon Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

This study will evaluate the safety, tolerability and efficacy of AT-1501 in an immunomodulation regimen in adult patients with T1D undergoing an islet cell transplant.

Timeline

Start
2022-09-30
Primary completion
2024-08
Completion
2028-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Isolated cadaveric islet cells Cell therapy Other
Subject Tegoprubart Monoclonal antibody Intravenous