drugset / Trial / NCT05485974

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

NCT05485974 ↗

Phase 1 Active not recruiting 44 enrolled HUYABIO International, LLC.
NaSequentialOpen-labelTreatment

Summary

A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS G12C mutation to determine the maximum tolerated dose and recommended Phase II dose of HBI-2438 and characterize its pharmacokinetic profile.

Timeline

Start
2022-08-01
Primary completion
2026-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject HBI-2438 Unknown — Oral