Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of Knee

Summary

Osteoarthritis (OA) is the most common degenerative joint disease, affecting more than 25% of the population . Knee OA is an insidious disease related to structural changes in the joint over many years. Progressive articular damage results in a loss of the extracellular matrix of cartilage in addition to changes in subchondral bone. Duloxetine, a selective serotonin, and norepinephrine reuptake inhibitor, it seems to be effective in treating neuropathic and chronic pain conditions.

Timeline

Start

2022-08-20

Primary completion

2022-12-29

Completion

2023-01-02

Drugs

Indications