drugset / Trial / NCT05486065

A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight

NCT05486065

Phase 2 Completed 245 enrolled Novo Nordisk A/S
RandomizedParallel-groupDouble-blindTreatment

Summary

This study compares how three doses of semaglutide work in participants with type 2 diabetes (T2D) and overweight who are taking metformin. The study will look mainly at how well participant's blood sugar and participant's body weight are controlled when they are taking the study medicine at different doses. Participants will either get semaglutide \[2 milligrams (mg), 8 mg, or 16 mg\] or semaglutide placebo (a dummy medicine). Participants will take the study medicine with an injection pen called NovoPen®4. The injection pen is a medical tool with a needle used to inject the study medicine under the skin. The study will last for about 52 weeks. Participants will have 13 clinic visits and 4 phone calls.

Timeline

Start
2022-08-08
Primary completion
2023-10-12
Completion
2023-12-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Semaglutide Peptide 2 mg Subcutaneous
Subject Semaglutide Peptide 8 mg Subcutaneous
Subject Semaglutide Peptide 16 mg Subcutaneous