drugset / Trial / NCT05489991

A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

NCT05489991 ↗

Phase 1/2 Terminated 1 enrolled Tceleron Therapeutics, Inc.
NaSequentialOpen-labelTreatment

Summary

An open-label, multi-center, Phase 1/2 study to determine the safety, tolerability, and feasibility of dosing adult patients with mCRPC with genetically modified autologous T-cells (TmPSMA-02) engineered to express a CAR capable of recognizing the tumor antigen prostate-specific membrane antigen (PSMA) and activating the T-cell.

Timeline

Start
2022-09-06
Primary completion
2023-05-03
Completion
2023-05-03

Outcome

Outcome not reported

Stopped: “Study was stopped Sponsor discretion. No patients were dosed.”

Drugs

EvaluationDrugModalityDoseRoute
Subject TmPSMA-02 Cell therapy — Intravenous

Indications