drugset / Trial / NCT05489991
A Study of TmPSMA-02 Chimeric Antigen Receptor (CAR) T-cells in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
NaSequentialOpen-labelTreatment
Summary
An open-label, multi-center, Phase 1/2 study to determine the safety, tolerability, and feasibility of dosing adult patients with mCRPC with genetically modified autologous T-cells (TmPSMA-02) engineered to express a CAR capable of recognizing the tumor antigen prostate-specific membrane antigen (PSMA) and activating the T-cell.
Timeline
- Start
- 2022-09-06
- Primary completion
- 2023-05-03
- Completion
- 2023-05-03
Outcome
Outcome not reported
Stopped: “Study was stopped Sponsor discretion. No patients were dosed.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | TmPSMA-02 | Cell therapy | — | Intravenous |