Effect of Perioperative Gabapentin on Postoperative Opioid Requirements

Phase 4 Completed 114 enrolled Indiana University

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to determine if preoperative gabapentin is noninferior to preoperative and postoperative gabapentin for pain control in patients undergoing surgery for pelvic organ prolapse.

Timeline

Start: 2021-07-27
Primary completion: 2023-06-17
Completion: 2023-07-05

Publications

Guanzon A, Hale D, Morse D, Bhamidipalli SS, Guise D, Hamner J, Heit M. Perioperative Gabapentin and Opioid Requirements: A Randomized Controlled Trial. Urogynecology (Phila). 2026 Jun 15. doi: 10.1097/SPV.0000000000001891. Online ahead of print.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Gabapentin	Small molecule	—	—

Indications

No indication recorded.