drugset / Trial / NCT05494957
Clinical Study of New Intensive Treatment Regimen for Severe Nontuberculous Mycobacterial Pulmonary Disease
Phase 4
Unknown
40 enrolled
Shanghai Pulmonary Hospital, Shanghai, China
Anhui Chest Hospital · collabHuashan Hospital · collabNo.85 Hospital, Changning, Shanghai, China · collabShanghai Public Health Clinical Center · collabShanghai Pudong New Area Pulmonary Hospital, China · collabThe Sixth People's Hospital of Zhengzhou · collab
NaSingle-groupOpen-labelTreatment
Summary
Investigators have selected a number of new drugs, including bedaquiline, to form a regimen to conduct clinical studies for the treatment of severe NTM lung disease.
Timeline
- Start
- 2022-08-05
- Primary completion
- 2024-08-05
- Completion
- 2025-08-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Amikacin | Small molecule | — | — |
| Background | Bedaquiline | Small molecule | — | — |
| Background | Clofazimine | Small molecule | — | — |
| Background | Linezolid | Other / unclassified | — | — |
| Background | Tigecycline | Small molecule | — | — |