drugset / Trial / NCT05497674
Effects of Rifampicin and Probenecid On The Pharmacokinetic Profile Of Rongliflozin In Healthy Subjects
Non-randomizedParallel-groupOpen-labelBasic science
Summary
This is a phase I, open-label, fixed-sequence study in healthy Chinese subjects, performed at a single study centre. Cohort A will assess the Pharmacokinetic (PK) profile of rongliflozin when administered alone and the combination with rifampicin; Cohort B will assess the PK profile of rongliflozin when administered alone and combination with probenecid.
Timeline
- Start
- 2022-02-21
- Primary completion
- 2022-07-22
- Completion
- 2023-02-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Probenecid | Small molecule | — | — |
| Subject | Rifampin | Small molecule | — | — |
| Subject | Rongliflozin | Small molecule | — | Oral |