drugset / Trial / NCT05502250

Tislelizumab, Gemcitabine and Cisplatin for R/R Hodgkin Lymphoma Followed by Tislelizumab Consolidation in Patients in Metabolic Complete Remission

NCT05502250 ↗

Phase 2 Active not recruiting 75 enrolled HOVON Foundation Danish Lymphoma Group · collab
NaSingle-groupOpen-labelTreatment

Summary

This trial investigates the efficacy and safety of the drug tislelizumab in combination with chemotherapy as a treatment for patients with R/R HL. Tislelizumab is given in combination with chemotherapy (gemcitabine and cisplatin) followed by consolidation with tislelizumab alone. The study primary question is whether this strategy works as well as the standard treatment with intensive chemotherapy and autologous stem cell transplant.

Timeline

Start
2023-07-14
Primary completion
2028-03
Completion
2031-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified — Intravenous
Subject Gemcitabine Small molecule — Intravenous
Subject Tislelizumab Monoclonal antibody — Intravenous

Indications