drugset / Trial / NCT05505747
Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair
RandomizedParallel-groupTriple-blindTreatment
Summary
Arthroscopic meniscal procedures are the most commonly performed orthopaedic procedure in the U.S. affecting 15% of Americans ages 10-65 years. Meniscus injury is also known to increase the risk of posttraumatic osteoarthritis (PTOA). The current randomized clinical trial will test a novel intervention after meniscal repair that combines an oral senolytic fisetin and real-time biofeedback program to restore joint loading and subsequent return to activity.
Timeline
- Start
- 2025-07
- Primary completion
- 2026-02
- Completion
- 2026-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fisetin | Small molecule | 20 mg/kg | Oral |
Indications
No indication recorded.