Safety, Tolerability and Prophylactic Antiviral Activity of Neumifil Against Influenza Via a Human Viral Challenge Model

Summary

Study to assess the efficacy and safety of a multiple dose regimen and a single dose regimen of intranasal Neumifil, administered prior to challenge with Influenza virus in healthy adult participants

Timeline

Start

2022-08-12

Primary completion

2023-05-04

Completion

2023-05-04

Publications

• Kitson G, Byford M, Cass L, Howat D, Kohn B, Bisquera A, Catchpole A, Noulin N, Thomson D. A Phase II, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of HEX17, a Novel Broad-Spectrum Antiviral Drug, in a Controlled Human Infection Model of Influenza Challenge. Infect Dis Ther. 2025 Aug;14(8):1697-1714. doi: 10.1007/s40121-025-01179-2. Epub 2025 Jul 2.

Drugs

Indications