drugset / Trial / NCT05507632

Donafenib Plus Sintilimab in Combination With TACE in Patients With Unresectable Hepatocellular Carcinoma

NCT05507632

Phase 2 Active not recruiting 48 enrolled Nanfang Hospital, Southern Medical University
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of Donafenib plus Sintilimab in combination with transarterial chemoembolisation (TACE) in patients with unresectable hepatocellular carcinoma(HCC).

Timeline

Start
2022-08-18
Primary completion
2026-03-26
Completion
2026-12-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Donafenib Small molecule
Subject Sintilimab Monoclonal antibody