drugset / Trial / NCT05512208

A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

NCT05512208

Phase 2 Recruiting 55 enrolled University of Oklahoma Verastem, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this research is to test the effectiveness and safety of the study drugs (VS-6766 and defactinib), and see what effects (good and bad) these drugs have on the patients with endometrioid cancer, mucinous ovarian cancer, high-grade serous ovarian cancer, or solid gynecological cancer.

Timeline

Start
2023-02-06
Primary completion
2027-12
Completion
2029-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Avutometinib Small molecule 3.2 mg Oral
Subject Defactinib Small molecule 200 mg Oral