drugset / Trial / NCT05514444

Study of MK-4464 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced/Metastatic Solid Tumors (MK-4464-001)

NCT05514444 ↗

Phase 1 Completed 64 enrolled Merck Sharp & Dohme LLC
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to assess the safety, pharmacokinetics, and preliminary efficacy of MK-4464 as monotherapy and in combination with pembrolizumab in participants with advanced/metastatic solid tumors.

Timeline

Start
2022-09-25
Primary completion
2025-09-18
Completion
2025-09-18

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-4464 Unknown — Intravenous
Background 89Zr-MK-4464 Unknown — Intravenous
Background Pembrolizumab Monoclonal antibody 200 mg Intravenous

Indications