drugset / Trial / NCT05515731

Platelet Rich Plasma as a Treatment For Resistant Corneal Ulcers

NCT05515731 ↗

Phase 4 Completed 14 enrolled Alaa Gamal Al-Azhar University · collab
NaSingle-groupOpen-labelTreatment

Summary

This prospective study involved 14 patients aged \> 18 years with RCUs not responding to conventional treatment. All patients were treated with E-PRP drops (one drop), preservative-free artificial tears, antibiotic eye drop four times daily and systemic vitamin A once daily for one month. All patients were examined at 1, 2, 4, 6 and 8 weeks after the treatment initiation. In each visit, the following parameters were assessed: best corrected visual acuity (BCVA), anterior segment, corneal healing, condition of the conjunctiva, presence of abnormal discharge and symptoms reported.

Timeline

Start
2021-01-01
Primary completion
2021-12-31
Completion
2021-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Autologous platelet-rich plasma (PRP) eye drops Other / unclassified — Topical

Indications