drugset / Trial / NCT05519449
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Non-randomizedSequentialOpen-labelTreatment
Summary
This study is a first-in-human, Phase 1, open-label, multicenter study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and the preliminary efficacy of JANX007 in adults with metastatic castration-resistant prostate cancer (mCRPC).
Timeline
- Start
- 2022-09-15
- Primary completion
- 2027-07
- Completion
- 2028-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | JANX007 | Unknown | — | Intravenous |
| Background | Darolutamide | Other / unclassified | — | Oral |