drugset / Trial / NCT05519449

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

NCT05519449

Phase 1 Recruiting 272 enrolled Janux Therapeutics
Non-randomizedSequentialOpen-labelTreatment

Summary

This study is a first-in-human, Phase 1, open-label, multicenter study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and the preliminary efficacy of JANX007 in adults with metastatic castration-resistant prostate cancer (mCRPC).

Timeline

Start
2022-09-15
Primary completion
2027-07
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject JANX007 Unknown Intravenous
Background Darolutamide Other / unclassified Oral