drugset / Trial / NCT05528367

Tirelizumab in Combination With Chemoradiation in Patients With Unresectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

NCT05528367

Phase 2 Unknown 33 enrolled Zhejiang Cancer Hospital
NaSingle-groupOpen-labelPrevention

Summary

To evaluate the efficacy and safety of chemoradiotherapy combined with tirelizumab in the treatment of initial unresectable locally advanced gastric cancer or gastroesophageal junction cancer.

Timeline

Start
2022-01-01
Primary completion
2024-06-30
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Nab-PTX Unknown 100 mg/m2
Subject Nab-PTX Unknown 100 mg
Subject Nab-PTX Unknown 130 mg/m2
Subject S-1 Small molecule 80 mg
Subject S-1 Small molecule 100 mg
Subject S-1 Small molecule 120 mg
Subject Tirelizumab Monoclonal antibody 200 mg

Indications