drugset / Trial / NCT05529316

A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma

NCT05529316

Phase 2 Active not recruiting 150 enrolled Agenus Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is an open-label, 2-part, Phase 2, multicenter study to evaluate the efficacy, safety, tolerability, and pharmacokinetic profiles of botensilimab as monotherapy and in combination with balstilimab in participants with advanced cutaneous melanoma refractory to checkpoint inhibitor therapy.

Timeline

Start
2022-12-12
Primary completion
2028-02
Completion
2028-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Balstilimab Monoclonal antibody Intravenous
Subject Botensilimab Monoclonal antibody Intravenous

Indications