Ozone Gel Application in Controlled Type 2 Diabetic Patients With Periodontitis

Summary

The adjunctive topical subgingival application ozone gel creates a great improvements in the clinical, bacteriological and immunological parameters over the gold standard of periodontal pocket treatment alone.

Timeline

Start

2022-10-15

Primary completion

2023-02-10

Completion

2023-08-02

Outcome

Missed primary endpoint

paper In contrast, intergroup differences revealed no statistically significant difference across the various time intervals (p > 0.05). PMID 39587593 ↗

Publications

• Barahim AA, Shemais N, Mousa A, Darhous M. Clinical and radiographic evaluation of non-surgical therapy with and without ozone gel application in controlled type 2 diabetic patients with periodontitis: a randomized controlled clinical trial. BMC Oral Health. 2024 Nov 25;24(1):1435. doi: 10.1186/s12903-024-05212-7.

Drugs

Indications