drugset / Trial / NCT05543837
Capsaicin for Cerebral Perfusion Augmentation
Phase 2
Completed
20 enrolled
Mexican Social Security Institute
Centenario Hospital Miguel Hidalgo · collab
Non-randomizedSingle-groupOpen-labelOther
Summary
To determine the effect of capsaicin upon serial transcranial Doppler (TCD) markers of cerebral blood flow (CBF). Methods Serial TCD testing in 30 participants with cerebrovascular risk factors. Capsaicin doses .66 and .99 μMol. Outcomes: peak systolic and end-diastolic velocities in the middle cerebral artery (MCA), mean velocity (MV), pulsatility index (PI), CBF index, arterial pressure, and perceived pungency (PP) in five minutes intervals up to 20 minutes.
Timeline
- Start
- 2022-09-20
- Primary completion
- 2022-09-30
- Completion
- 2023-02-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Capsaicin | Small molecule | 0.66 unknown | Topical |
| Subject | Capsaicin | Small molecule | 0.99 unknown | Topical |