drugset / Trial / NCT05549297

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

NCT05549297

Phase 3 Recruiting 540 enrolled Immunocore Ltd
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator choice (including clinical trials of investigational agents, salvage therapy per local standard of care \[SoC\], best supportive care \[BSC\] on protocol survivor follow up) in patients with advanced non-ocular melanoma.

Timeline

Start
2022-12-19
Primary completion
2028-03
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody
Subject Tebentafusp Protein / enzyme biologic

Indications