drugset / Trial / NCT05550025

TACE Combined With Camrelizumab and Apatinib in the Treatment of Advanced Liver Cancer

NCT05550025 ↗

NaSingle-groupOpen-labelTreatment

Summary

This study was designed to evaluate the effectiveness and safety of TACE(transcatheter arterial chemoembolization) combined with Apatinib and Camrelizumab for Hepatocellular Carcinoma. The primary outcome measure is to evaluate the objective response rate (ORR) of the therapy for Hepatocellular Carcinoma. The secondary Outcome measures include the duration of response (DOR), disease control rate (DCR), progression-free survival rate (PFSR) \[ Time Frame: 6- and 12-month\], overall survival rate (OSR) \[ Time Frame: 6- and 12-month\], the median progression-free survival time (mPFS) and median overall survival time (mOS) of the therapy for Hepatocellular Carcinoma. Moreover, this study aims to assess the safety and tolerability of the Therapy for Hepatocellular Carcinoma.

Timeline

Start
2021-12-17
Primary completion
2023-11-11
Completion
2024-02-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg —
Subject Rivoceranib Small molecule 250 mg Oral