drugset / Trial / NCT05553093
Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 Diabetes
RandomizedParallel-groupOpen-labelTreatment
Summary
The effects of Tirzepatide and Insulin Glargine on glucose and lipid metabolism and inflammation in patients with type 2 diabetes mellitus. Effects of Tirzepatide on the occurrence and development of cognitive impairment in diabetic patients and its associated pattern of changes in brain neural network characteristics.
Timeline
- Start
- 2022-03-15
- Primary completion
- 2023-12-31
- Completion
- 2027-10-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tirzepatide | Peptide | 5 mg | Other |
| Subject | Tirzepatide | Peptide | 10 mg | Other |
| Subject | Tirzepatide | Peptide | 15 mg | Other |
| Comparator | insulin glargine | Protein / enzyme biologic | 6 iu | Other |