drugset / Trial / NCT05558280

Qarziba for Patients in Relapsed/Refractory High-grade Osteosarcoma

NCT05558280

Phase 2 Suspended 22 enrolled Prof. Franca Fagioli
NaSingle-groupOpen-labelTreatment

Summary

Limited progress has been made in identifying novel targets that may be therapeutic for Osteosarcoma(OS) and there remains an urgent need for the development of new agents that are effective in improving survival. From this perspective, repurposing already proven targets in other tumors may offer new opportunities for OS in children and young adults. Anecdotal evidence of anti-GD2 therapy exists in OS from prior Phase 1 trials that included patients with OS.

Timeline

Start
2023-11-30
Primary completion
2025-12-15
Completion
2026-12-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Dinutuximab Monoclonal antibody 14 mg/m2 Intravenous