drugset / Trial / NCT05561205

rTMS for Apathy Clinical Trial

NCT05561205

Recruiting 10 enrolled Sunnybrook Health Sciences Centre
Non-randomizedParallel-groupSingle-blindTreatment

Summary

Apathy is a common, early, and disabling symptom in dementias and mild behavioural impairment such as Alzheimer's disease (AD) and is characterized by lack of interest and enthusiasm. Both repetitive transcranial magnetic stimulation (rTMS), a form of non-invasive brain stimulation, and methylphenidate, a medication, have been shown to improve apathy. This pilot study will investigate rTMS as a treatment for apathy in neurocognitive disorders and mild behavioural impairment in individuals receiving methylphenidate and individuals not receiving medication for apathy.

Timeline

Start
2023-02-09
Primary completion
2026-12-01
Completion
2026-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylphenidate Small molecule