A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Summary

This study will test the safety of a drug called PF-08046049/SGN-BB228 in participants with melanoma and other solid tumors that are hard to treat or have spread through the body. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. This study will have 3 parts. Parts A and B of the study will find out how much PF-08046049/SGN-BB228 should be given to participants. Part C will use the information from Parts A and B to see if PF-08046049/SGN-BB228 is safe and if it works to treat solid tumor cancers.

Timeline

Start

2023-01-03

Primary completion

2026-06-01

Completion

2026-06-01

Outcome

Outcome not reported

Stopped (Business): “The trial was terminated for strategic reasons. The decision was not based on any safety concerns.”

Drugs

Indications