Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents

Summary

This study will examine if brain insulin resistance is a feature of depression in humans using magnetic resonance imaging (MRI) measures sensitive to brain insulin action. This study will examine adolescents, as depression onset commonly occurs during this age, and the impacts of cumulative medication exposure and other lifestyle-related confounds are also lower in this age group, improving our ability to understand the underlying biology.

Timeline

Start

2021-09-01

Primary completion

2025-05-13

Completion

2025-05-13

Drugs

Indications